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DOI 10.1007/s00213-008-1443-x

Медицинская библиотека · Psychopharmacology · 2009

Novice drivers' performance after different alcohol dosages and placebo in the divided-attention steering simulator (DASS).

Verster Joris C, Wester Anne E, Goorden Maartje, van Wieringen Jan-Peter, Olivier Berend, Volkerts Edmund R

СтатьяРандомизированное исследованиеПоддержка исследования: вне правительства СШАПеревод пока не подготовлен

Аннотация

RATIONALE: The divided-attention steering simulator (DASS) is designed to measure lane-keeping (i.e., a tracking task using a steering wheel) while performing a secondary visual task (responding to digits that appear in the corners of the computer screen). Some studies have already used the DASS, but the magnitude of impairment is difficult to interpret because reference values are lacking.

OBJECTIVE

To examine the magnitude of impairment after administration of four different dosages of alcohol and placebo.

MATERIALS AND

METHODS

Thirty-two healthy young adults participated in this randomized, single-blind crossover trial. Subjects received alcohol to gain a blood alcohol concentration (BAC) of 0.02%, 0.05%, 0.08%, and 0.10% or alcohol-placebo. Sixteen subjects performed a 30-min test in DASS (dual-task condition). Outcome measures were steering error, reaction time, and percentage of errors. Sixteen other subjects performed the test without performing the secondary peripheral task (single-task condition).

RESULTS

Twenty-eight subjects (novice drivers; drivers' license up to 5 years) were included in the analyses. Dose-dependent impairment was found in both the single-task condition (F ((4,11)) = 10.86, p < 0.001) and the dual-task condition (F ((4,9)) = 5.58, p < 0.015). Performance at all BAC levels differed significantly (p < 0.05) from alcohol-placebo, except BAC 0.02%. With increasing BAC levels, subjects made more errors and reacted slower on the peripheral visual search task, but these effects did not reach significance.

CONCLUSION

With increasing BAC, dose-dependent impairment was found. The DASS seems to be a suitable divided-attention task that is useful in psychopharmacological research and training of novice drivers.

Для цитирования: Verster Joris C, Wester Anne E, Goorden Maartje, van Wieringen Jan-Peter, Olivier Berend, Volkerts Edmund R. Novice drivers' performance after different alcohol dosages and placebo in the divided-attention steering simulator (DASS).. Psychopharmacology. 2009. DOI: 10.1007/s00213-008-1443-x.

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