Intraocular pressure change during hemodialysis.

PURPOSE: To evaluate intraocular pressure (IOP) change through hemodialysis and examine other factors to affect IOP change in patients treated with hemodialysis.

DESIGN

Prospective, observational case series.

METHODS

IOP, blood pressure, and plasma colloid osmotic pressure (COP) were measured in 188 eyes of 95 patients receiving hemodialysis in Nantan General Hospital.

RESULTS

IOP significantly decreased after hemodialysis (P = 0.006). Body weight, systolic and diastolic blood pressure also decreased significantly (P < 0.001). COP significantly increased (P < 0.001). Change in IOP correlated negatively with COP change (OD; r = -0.196, OS; r = -0.339) and positively with change in body weight (OD; r = -0.278, OS; r = -0.357). IOP tended to increase after hemodialysis in patients receiving hemodialysis for more than 12 years.

CONCLUSIONS

IOP decrease during hemodialysis may be due to COP increase. Patients receiving hemodialysis for a long time are more likely to show IOP increase after hemodialysis.