[The effect on painful and silent myocardial ischemia of the preparations Efox and Efox Long in patients with stenocardia of effort].

The study of two novel drugs for management of both painful and silent myocardial ischemia isosorbide-5-mononitrate (IS-5-MN), efox, and its long-acting variant efox-long demonstrated that both drugs exerted noticeable antianginal effect at maximal concentration in blood. This was achieved by a single dose and course administration. The differences in the effects of the two dosage forms of IS-5-MN on painless ischemia may be explained by limited coronary reserves of anginal patients.