Left ventricular diastolic dysfunction in patients with angina decubitus.

OBJECTIVE

To investigate the relationship between left ventricular diastolic dysfunction and episodes of angina decubitus.

METHODS

The study population consisted of three groups, groups I (20 controls) had no cardiovascular diseases. Group II (20 patients) had coronary artery disease (CAD) without angina decubitus. Group III (24 cases with ejection fraction (EF) > 45%) were selected from 26 patients with angina decubitus.

RESULTS

Left ventriculography (LVG) showed that left ventricular (LV) first 1/3 filling fraction (1/3FF) was significantly reduced in groups III as compared with groups II and I (P < 0.01). Left ventricular end-diastolic pressure (LVEDP) significantly increased in patients with angina decubitus after LVG as compared with that before LVG (P < 0.01). However, there were no statistically differences in LVEDP, before and after LVG in both groups II and I.

CONCLUSIONS

Patients with angina decubitus have abnormalities of LV diastolic filling and decrease in LV compliance.