American journal of otolaryngology · 2022
"Incidentally discovered medullary thyroid carcinoma in the post-operative Graves' patient - A case report".
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Akin Ryan, Gilley David, Tassone Patrick
Аннотация
OBJECTIVE: To report a very rare case of incidentally discovered Medullary Thyroid Carcinoma after total thyroidectomy in a patient with Graves' disease, review available literature, and present readers with management information.
RESULTS: Medullary Thyroid Carcinoma in the setting of Graves' disease is a rare scenario. Only fifteen total cases besides ours has been described in literature, and only six other cases were incidentally discovered.
CONCLUSIONS: When Medullary Thyroid Carcinoma is incidentally discovered in the setting of Graves' disease, retroactive workup should begin with postoperative calcitonin, CEA level, testing for RET mutation, and a comprehensive neck ultrasound as soon as the diagnosis is made.
RESULTS: Medullary Thyroid Carcinoma in the setting of Graves' disease is a rare scenario. Only fifteen total cases besides ours has been described in literature, and only six other cases were incidentally discovered.
CONCLUSIONS: When Medullary Thyroid Carcinoma is incidentally discovered in the setting of Graves' disease, retroactive workup should begin with postoperative calcitonin, CEA level, testing for RET mutation, and a comprehensive neck ultrasound as soon as the diagnosis is made.