Expert review of gastroenterology & hepatology · 2026
Per-oral endoscopic myotomy (POEM) in achalasia: why length matters.
СтатьяОбзорНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Kang Anthony J, Pandolfino John E, Aadam A Aziz
Аннотация
INTRODUCTION: Per-oral endoscopic myotomy (POEM) is a minimally-invasive, effective treatment option in patients with non-spastic and spastic achalasia, and is continuously evolving toward a personalized, tailored approach for patients.
AREAS COVERED: This article reviews the procedural aspects of POEM, its efficacy in the treatment of non-spastic and spastic achalasia, adverse events, and how it compares to other first-line therapies including pneumatic dilation and laparoscopic Heller myotomy with partial fundoplication. It also describes the evolution of tailored therapy in patients, including short-tailored myotomy in non-spastic achalasia and manometry-directed myotomy in spastic achalasia. This review is based on data from randomized controlled trials, systematic reviews, meta-analyses, and comparative studies from PubMed over the past 20 years, and primarily over the past 5-10 years.
EXPERT OPINION: POEM has continuously moved toward personalized medicine, offering tailored therapy to a patient's specific phenotype. Delivering effective therapy while minimizing the major disadvantages of POEM (e.g. gastroesophageal reflux, esophagitis, and blown-out myotomy) would be a milestone in achalasia therapy. A movement toward a short-tailored myotomy in non-spastic achalasia and manometry-directed therapy for spastic achalasia may provide these answers.
AREAS COVERED: This article reviews the procedural aspects of POEM, its efficacy in the treatment of non-spastic and spastic achalasia, adverse events, and how it compares to other first-line therapies including pneumatic dilation and laparoscopic Heller myotomy with partial fundoplication. It also describes the evolution of tailored therapy in patients, including short-tailored myotomy in non-spastic achalasia and manometry-directed myotomy in spastic achalasia. This review is based on data from randomized controlled trials, systematic reviews, meta-analyses, and comparative studies from PubMed over the past 20 years, and primarily over the past 5-10 years.
EXPERT OPINION: POEM has continuously moved toward personalized medicine, offering tailored therapy to a patient's specific phenotype. Delivering effective therapy while minimizing the major disadvantages of POEM (e.g. gastroesophageal reflux, esophagitis, and blown-out myotomy) would be a milestone in achalasia therapy. A movement toward a short-tailored myotomy in non-spastic achalasia and manometry-directed therapy for spastic achalasia may provide these answers.