[Clinical polymorphism of depression and cognitive deficit].

OBJECTIVE

To study the relation between psychometric assessment of depression and parameters of cognitive functioning.

MATERIAL AND

METHODS

Authors examined 90 patients (75 women and 15 men), aged from 20 to 75 years, with depression. Twenty-five patients were diagnosed with depressive episode, 40 with recurrent depression, 6 with bipolar depression, 8 with dysthymia and 11 with sub-depression. The diagnosis was made according to ICD-10 criteria. Its were used the following scales: HAMD, BDI, MMPI, ACE-R.

RESULTS

The nosographic differentiation of depression only partially reflected the presence of cognitive deficit. An analysis of depressive syndromes identified psychometrically revealed that cognitive deficit on ACE-R was correlated with behavioral stereotypes on MMPI but not with scores on HAM-D and BDI.

CONCLUSION

Observational criteria (registration of abnormal behavioral stereotypes) should be used in assessment of cognitive deficit in patients with depression. This fact should be also taken into consideration in the studies of antidepressant effects on cognitive function.