[Inborn Error of Metabolism].

Inborn errors of metabolism are single-gene disorders in which metabolic abnormalities involving amino acids, organic acids, fatty acids, glycolipids, complex carbohydrates, glycoproteins, and metals cause various neurological symptoms. Although most cases occur in childhood, many diseases have been reported to have adult onset. Significant progress has been made in diagnostic and therapeutic techniques, with early detection through screening and the development of treatments, such as dietary therapy and enzyme replacement therapy.