The vitiligo is the human skin's pigmentary challenge still: an up-to-date review.

The vitiligo is a cutaneous pigmentary disease. It is one of the most common skin conditions challenging most dermatologists all over the world. The purpose of the study is to shed a light on available data of this skin lesion regarding its epidemiology, pathogenesis, etiology and genetic causes. Additionally theories and hypotheses related to its occurrence and clinical characteristics of various distinguishable types are considered. The diagnosis and treatment of this skin disorder using different medications and management lines or procedures, particularly recently discovered ones, may positively input into treatment of these skin disorders. The article is based on comprehensive data obtained from such well-known scientific databases as Web of Science, Medline, EMBASE, Pubmed Central, PubMed, Scopus, and Cochrane Library.