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Canadian journal of ophthalmology. Journal canadien d'ophtalmologie · 2021

Clinical characteristics, rates of blindness, and geographic features of PACD in China.

СтатьяМногоцентровое исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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Zhang Hui, Cao Kai, Jia Hongyan, Li Liang, Hu Jianping, Liang Jing, Song Jing, Wang Hui, Zhao Aiping, Duan Xiaoming, Fan Sujie, Wang Feng, Su Ying, Ha Shaoping, Duan Xuanchu, Yu Jingni, Zhao Chunmei, Tang Guangxian, Su Yufang, Cai Hongying, Gao Jianlu, Qu Yanbing, Lu Peng, Xie Xiaobin, Zhao Junhong, Tang Li, Liu Danyan, Liu Wei, Zhang Min, Fang Aiwu, Qu Bo, Dai Weijia, Zhong Hua, Zhang Xueling, Wu Zuohong, Zhai Gang, Lyu Hongbin, Xie Lin, Li Haijun, Zheng Yajuan, Li Ning, Li Kaijun, Xie Guijun, Qu Hongbo, Yu Jinqiang, Liang Liang, Zhu Min, Wang Xuemei, Ma Xiang, Zeng Liuzhi, Liu Xuyang, Zhang Yong, Zhang Yuyan, Yu Fanglei, Zhu Yihua, Cheng Sumian, Yu Min, Li Jingmin, Zhang Yinong, Liu Ping, Wu Zhihong, Zhang Xiuzhi, Kuo Debbie, Wang Ningli, Qiao Chunyan

Аннотация

OBJECTIVE: To analyze the rates of blindness with the demographics and clinical characteristics of patients with primary angle-closure disease (PACD) to provide a comprehensive epidemiologic reference in China.

METHODS: A retrospective analysis was conducted in the Chinese Glaucoma Study Consortium database, which is a national multicenter glaucoma research alliance of 111 hospitals participating between December 21, 2015 and September 9, 2018. The diagnosis of PACD was made by qualified physicians through examination. Comparison of sex, age, family history, subtypes of PACD, and blindness were analyzed.

RESULTS: A total of 5762 glaucoma patients were included, of which 4588 (79.6%) had PACD. Of PACD patients, 72.1% were female with the sex ratio (F/M) of 2.6, and the average age of patients was 63.8±9.3 years with the majority between 60 and 70 years. Additionally, 30% of these patients had low vision in one eye, 8.8% had low vision in both eyes, 1.7% had blindness in one eye, and 0.3% had blindness in both eyes. There were statistical differences with regards to age between male and female patients with PACD, with male patients being older on average. Primary angle-closure glaucoma was more commonly diagnosed in males (60%) compared to females (35.9%), whereas acute primary angle closure (APAC) was more commonly diagnosed in females (54.3%) compared to males (37.7%). The visual acuity in APAC patients was lower and the rate of low vision and blindness was higher than other subtypes.

CONCLUSION: PACD was the major type of glaucoma in Chinese hospitals. There were more female patients with PACD, mostly between 60 and 70 years old, with higher rates of APAC in women. APAC resulted in the worst visual outcomes of all PACD subtypes.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты