Prior sleep problems and adverse post-traumatic neuropsychiatric sequelae of motor vehicle collision in the AURORA study.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Neylan Thomas C, Kessler Ronald C, Ressler Kerry J, Clifford Gari, Beaudoin Francesca L, An Xinming, Stevens Jennifer S, Zeng Donglin, Linnstaedt Sarah D, Germine Laura T, Sheikh Sophia, Storrow Alan B, Punches Brittany E, Mohiuddin Kamran, Gentile Nina T, McGrath Meghan E, van Rooij Sanne J H, Haran John P, Peak David A, Domeier Robert M, Pearson Claire, Sanchez Leon D, Rathlev Niels K, Peacock William F, Bruce Steven E, Joormann Jutta, Barch Deanna M, Pizzagalli Diego A, Sheridan John F, Harte Steven E, Elliott James M, Hwang Irving, Petukhova Maria V, Sampson Nancy A, Koenen Karestan C, McLean Samuel A
Аннотация
METHODS: A total of 666 AURORA patients completed self-report assessments in the ED and at 2 and 8 weeks after MVC. Peritraumatic distress, peritraumatic dissociation, and pre-MVC sleep characteristics (insomnia, nightmares, daytime sleepiness, and sleep duration in the 30 days before the MVC, trait sleep stress reactivity) were assessed retrospectively in the ED. The survey assessed acute stress disorder (ASD) and MDE at 2 weeks and at 8 weeks assessed PTSD and MDE (past 30 days). Control variables included demographics, MVC characteristics, and retrospective reports about PTSD and MDE in the 30 days before the MVC.
RESULTS: Prevalence estimates were 41.0% for 2-week ASD, 42.0% for 8-week PTSD, 30.5% for 2-week MDE, and 27.2% for 8-week MDE. Pre-MVC nightmares and sleep stress reactivity predicted 8-week PTSD (mediated through 2-week ASD) and MDE (mediated through the transition between 2-week and 8-week MDE). Pre-MVC insomnia predicted 8-week PTSD (mediated through 2-week ASD). Estimates of population attributable risk suggest that blocking effects of sleep disturbance might reduce prevalence of 8-week PTSD and MDE by as much as one-third.
CONCLUSIONS: Targeting disturbed sleep in the immediate aftermath of MVC might be one effective way of reducing MVC-related PTSD and MDE.