British journal of clinical pharmacology · 2007
National underuse of anti-thrombotic therapy in chronic atrial fibrillation identified from digoxin prescribing.
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Mahmud Azra, Bennett Kathleen, Okechukwu Ifeanyi, Feely John
Аннотация
AIMS: To examine if appropriate antithrombotic therapy in atrial fibrillation is implemented nationally.
METHODS: Using prescriptions for digoxin as a surrogate for atrial fibrillation, we identified its coprescription with antithrombotic therapy, aspirin or warfarin in a national prescribing database in 27 571 patients over 45 years old.
RESULTS: Proportionately significantly more men were on warfarin, and use in those >75 years old was three times less than in those <65 years. Reluctance to use antithrombotics was confirmed in a postal survey.
CONCLUSION: Data suggest a missed opportunity to prevent stroke with women and those >75 years old least likely to receive warfarin.
METHODS: Using prescriptions for digoxin as a surrogate for atrial fibrillation, we identified its coprescription with antithrombotic therapy, aspirin or warfarin in a national prescribing database in 27 571 patients over 45 years old.
RESULTS: Proportionately significantly more men were on warfarin, and use in those >75 years old was three times less than in those <65 years. Reluctance to use antithrombotics was confirmed in a postal survey.
CONCLUSION: Data suggest a missed opportunity to prevent stroke with women and those >75 years old least likely to receive warfarin.