World neurosurgery · 2018
Microvascular Brainstem Ischemia After Vestibular Schwannoma Surgery: A Clinical and Microanatomic Study.
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Hollon Todd C, Savastano Luis E, Argersinger Davis P, Quint Douglas J, Thompson B Gregory
Аннотация
OBJECTIVE: To identify a potential microvascular etiology in patients who underwent vestibular schwannoma surgery (VSS) complicated by postoperative microvascular brainstem ischemia.
METHODS: Charts were retrospectively reviewed of all patients who had an MRI within 14 days of VSS in years 2005-2016. Patient characteristics, preoperative and postoperative imaging features, clinical course and potential predictors of brainstem ischemia were recorded. Cadaveric dissections of 4 cerebellopontine angle (CPA) cisterns with focus on the anterior inferior cerebellar artery (AICA) microvascular were also performed to identify candidate vessels and potential etiology.
RESULTS: Fifty-four of 258 patients had an MRI within 14 days of VSS. Retrosigmoid approach was used in 61.1% of patients, translabyrinthine approach in 25.9%, and middle fossa approach in 13.0%. Four patients (7.4%) had acute microvascular ischemia involving the middle cerebellar peduncle (MCP) adjacent to the cranial nerve (CN) VII-VIII complex demonstrated on postoperative MRI. A statistically significant association was found between the translabyrinthine approach and acute brainstem ischemia (odds ratio, 10.6; 95% confidence interval, 1.004-112.7). Dissection of CPAs revealed 10-20 perforating arteries per specimen originating from the lateral pontine and the flocculopeduncular segments of the AICA. Most microvessels travelled in retrograde fashion along the anteroinferior surface of the CN VII-VIII complex to perforate the cisternal surface of the MCP. No patient had residual or delayed neurologic deficits related to brainstem ischemia at final follow-up.
CONCLUSIONS: While effort should be made to preserve perforating vessels, microvascular brainstem ischemia is often asymptomatic and did not lead to permanent neurologic deficits in our series.
METHODS: Charts were retrospectively reviewed of all patients who had an MRI within 14 days of VSS in years 2005-2016. Patient characteristics, preoperative and postoperative imaging features, clinical course and potential predictors of brainstem ischemia were recorded. Cadaveric dissections of 4 cerebellopontine angle (CPA) cisterns with focus on the anterior inferior cerebellar artery (AICA) microvascular were also performed to identify candidate vessels and potential etiology.
RESULTS: Fifty-four of 258 patients had an MRI within 14 days of VSS. Retrosigmoid approach was used in 61.1% of patients, translabyrinthine approach in 25.9%, and middle fossa approach in 13.0%. Four patients (7.4%) had acute microvascular ischemia involving the middle cerebellar peduncle (MCP) adjacent to the cranial nerve (CN) VII-VIII complex demonstrated on postoperative MRI. A statistically significant association was found between the translabyrinthine approach and acute brainstem ischemia (odds ratio, 10.6; 95% confidence interval, 1.004-112.7). Dissection of CPAs revealed 10-20 perforating arteries per specimen originating from the lateral pontine and the flocculopeduncular segments of the AICA. Most microvessels travelled in retrograde fashion along the anteroinferior surface of the CN VII-VIII complex to perforate the cisternal surface of the MCP. No patient had residual or delayed neurologic deficits related to brainstem ischemia at final follow-up.
CONCLUSIONS: While effort should be made to preserve perforating vessels, microvascular brainstem ischemia is often asymptomatic and did not lead to permanent neurologic deficits in our series.