Hypervitaminosis A in a child from megadosing.

Hypervitaminosis A developed in a 2-year-9-month-old boy after his mother gave him 6,338 IU/kg/day vitamin A for 5 months. The clinical features included irritability, xerosis of the skin and mucous membranes, pruritus, bone pain, and loss of ambulation. The bone scan showed involvement of more bones than was apparent on the roentgenograms. A prompt diagnosis depended on an accurate history of excessive vitamin intake, and the serum vitamin A level confirmed the diagnosis.