[A Case of Gastric Adenosquamous Carcinoma with Liver Invasion].

An 86-year-old man was referred to our hospital by his primary care physician because of epigastric pain. The patient was diagnosed with gastric cancer and underwent pyloric gastrectomy(D2 dissection and Roux-en-Y reconstruction)and partial hepatectomy. Based on the presence of squamous cell carcinoma and poorly differentiated adenocarcinoma components in postoperative pathological examination, a diagnosis of adenosquamous carcinoma(pT4bN2M0, pStage ⅢB)was made. Postoperative adjuvant chemotherapy with S-1+DTX was initiated; however, it was discontinued owing to severe general malaise. One year after surgery, the patient did not show any obvious signs of recurrence. Gastric adenosquamous carcinoma is a special type of gastric cancer with a relatively low incidence, accounting for approximately 0.4% of all gastric cancers. Here, we report a case of gastric adenosquamous carcinoma along with a review of the relevant literature.