[Takeuki and Nishimoto's syndrome: an angiographic and nefrographic study of one case (author's transl)].

Takeuki and Nishimoto's syndrome has been described as more common though not exclusive in the Japanese people; it occurs in the pediatric or young adult age. The clinical syndrome is most variable (transitory ischemic attacks or circulatory insufficiencies with permanent neurological deficit, as well as subarachnoid hemorrhage). Conversely, the angiographic syndrome is quite typical: I) stenosis of both internal carotid arteries and the anterior part of Willis circle; II) presence of an angiomatous net at the level of the basal ganglia; III) presence of several anastomosis between internal and external carotid arteries. The essential pathogenetic event seems to be the slow occlusion of the two internal carotid arteries and of the anterior part of the anterior part of the circle of Willis of unknown aetiology. The observations reported in the present article cover angiographic, nefrological, microbiological, metabolic and immunological studies in a clinical case of Takeuki and Nishimoto's syndrome. This was clinically revealed by a subarachnoid hemorhage, indicating that carotid stenosis may be a fairly selective process. The temporal evolution of such a process and the slow invasion of distal arterial segments support the interpretation of the process itself as not congenital.