Evaluation of linked-color imaging endoscopy combined with CAD EYE for the detection and characterization of right-sided colon polyps.

BACKGROUND AND STUDY AIMS: Optimizing polyp detection, in particular the right-sided colon polyps, is a challenge for endoscopists. This study aimed to evaluate the diagnostic value of LCI combined with CAD EYE in the detection and characterization of right-sided colon polyps.

PATIENTS AND

METHODS

Patients underwent colonoscopy with WLI up to the cecum and terminal ileum, followed by LCI combined with CAD EYE. All polyps detected were removed and subjected to histological examination.

RESULTS

116 patients were enrolled. Out of them, 66 patients had at least one polyp in their right-sided colon. Endoscopy utilizing LCI resulted in a significantly high additional polyp detection rate (APDR) of 25.9 % (95 % CI: 17.6-36.4 %) in the right colon compared to endoscopy with WLI. The APDRs were significantly higher for flat polyps, 43.5 % (95 % CI: 25.6-63.2 %), p = 0.023. The adenoma detection rate (ADR) was also increased, with APDRs for adenomatous polyps and sessile serrated polyps at 30.6 % (95 % CI: 18.0-46.9 %) and 66.7 % (95 % CI: 30-90.3 %), respectively (p = 0.022). The concordance in neoplasia detection utilizing LCI combined with CAD EYE and histological examination demonstrated substantial agreement between the two approaches, with Kappa values of 0.729 (p < 0.001).

CONCLUSION

LCI combined with CAD EYE emerged as a potential tool for characterizing right-sided colon polyps.