A corneal ring ulcer.

PURPOSE: The aim of this report is to present the case of a corneal ring ulcer that presented with diagnostic and therapeutic challenges.

OBSERVATIONS: A 52-year-old woman was referred by her retina doctors for ulceration of the left cornea and pain 8 days after intravitreal ranibizumab injection for diabetic macular edema. She had been treated with erythromycin ointment, topical moxifloxacin, and therapeutic soft contact lens, which she tolerated for less than 24 hours prior to referral. Visual acuity of the left eye was counting fingers. Slit lamp examination revealed a ring-shaped corneal ulcer.

CONCLUSIONS

Neurotrophic corneal ulceration can mimic acanthamoeba keratitis. Neurotrophic disease should be considered in patients with underlying risk factors in whom infectious etiology cannot be confirmed and/or who don't respond to anti-microbial therapy.