Journal of cosmetic dermatology · 2020
Nature-based botanical facial oil oxidative stress protection.
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Diana Draelos Zoe, Gunt Hemali, Levy Stanley B
Аннотация
INTRODUCTION: UV-induced oxidative skin stress leads to cutaneous photoaging. The objective of these 2 studies was to evaluate a nature-based botanical facial oil for the ability to decrease UV-induced oxidative skin stress.
METHODS: 22 females were enrolled in the UVA study, and 10 females were enrolled in the UVB study. Skin chemiluminescence induced by UVA exposure was measured at baseline and after 2 weeks of daily topical application of the nature-based facial oil was evaluated in study 1. In study 2, UVB-induced erythema was measured after 8 weeks of twice-daily topical application of the nature-based facial oil to a photoprotected site followed by skin biopsy to evaluate sunburn cell formation. In both studies, the treatment response was compared to the response on untreated skin.
RESULTS: The nature-based facial oil significantly reduced skin chemiluminescence following UVA exposure, demonstrating antioxidant activity. The nature-based facial oil also significantly reduced erythema formation following UVB exposure and resulted in reduced sunburn cell formation in 66.67% of subjects.
CONCLUSION: Topical nature-based facial oil can reduce UV-induced oxidative cutaneous damage.
METHODS: 22 females were enrolled in the UVA study, and 10 females were enrolled in the UVB study. Skin chemiluminescence induced by UVA exposure was measured at baseline and after 2 weeks of daily topical application of the nature-based facial oil was evaluated in study 1. In study 2, UVB-induced erythema was measured after 8 weeks of twice-daily topical application of the nature-based facial oil to a photoprotected site followed by skin biopsy to evaluate sunburn cell formation. In both studies, the treatment response was compared to the response on untreated skin.
RESULTS: The nature-based facial oil significantly reduced skin chemiluminescence following UVA exposure, demonstrating antioxidant activity. The nature-based facial oil also significantly reduced erythema formation following UVB exposure and resulted in reduced sunburn cell formation in 66.67% of subjects.
CONCLUSION: Topical nature-based facial oil can reduce UV-induced oxidative cutaneous damage.