How intolerance of uncertainty affects negative emotions in patients with primary glaucoma: a chain mediation model.

This study aims to investigate the relationship between intolerance of uncertainty and anxiety and depression in patients with primary glaucoma, and to analyze the mediating role of resilience and rumination as well as the chain-mediated effect in it. A total of 242 patients with primary glaucoma were enrolled in this study. Questionnaires were used to collect cross-sectional data on patients' intolerance of uncertainty, resilience, rumination, anxiety and depression. The chain mediation model was constructed by the IBM AMOS 26.0 statistical software and was tested by bias-corrected bootstrap method. Intolerance of uncertainty can directly affect anxiety and depression in patients with primary glaucoma, as well as indirectly through resilience and intrusive rumination. Moreover, resilience and intrusive rumination had a chain mediation effect between intolerance of uncertainty and anxiety and depression. Improving resilience and reducing intolerance of uncertainty and intrusive rumination are important interventions to improve anxiety and depression in patients with primary glaucoma.