Study on the effect of PICC in parenteral nutrition support for colorectal cancer.

OBJECTIVE

To study the effect of peripherally inserted central catheters (PICC) in parenteral nutrition support for patients with colorectal cancer.

METHODS

A total of 98 patients with colorectal cancer who were admitted to our hospital from January 2019 to June 2020 were selected into this study. The selected patients were randomly divided into two groups. Both groups were given parenteral nutrition support treatment. Patients who received central venous catheter (CVC) nutritional support therapy were included in the CVC group, and those who received PICC nutritional support were included in the PICC group (49 cases in each group). The two groups were compared in terms of the indicators of catheterization, the one-time success rate of catheterization and the occurrence of complications. The changes in nutritional status indicators and serum inflammatory factor levels of the two groups of patients before and after treatment were observed, and the tolerance of the two groups of patients to intubation was investigated.

RESULTS

The puncture time and catheter indwelling time in the PICC group were longer than those in the CVC group (P < 0.05); the complication rate was 14.29% in the PICC group, and 32.65% in the CVC group (P < 0.05); there were no statistically significant differences in TP, PA, ALB, and TF between the two groups before and after treatment (P > 0.05); after treatment, the expression of CRP and IL-6 in the PICC group was lower than that in the CVC group (P < 0.05). The CRP and IL-6 levels of patients in both groups were higher than those before treatment (P < 0.05); the tolerance of PICC group was higher than that of the CVC group (P < 0.05).

CONCLUSION

The application of PICC in parenteral nutrition support for colorectal cancer can improve the nutritional status of patients with few adverse reactions and high tolerance.