Update on the use of streptomycin therapy for Meniere's disease.

An update of our experiences in the treatment of Meniere's disease with intramuscular streptomycin sulfate reveals great success in relief of episodic vertigo. Hearing losses that existed before the treatment are generally stabilized and occasionally improved. Because of the considerable morbidity caused by arduous therapy, prolonged ataxia, and occasional oscillopsia, we recommend that the treatment be reserved for the bilateral disabling form of the disease.