Internal medicine (Tokyo, Japan) · 2017
The Impact of Human Parvovirus B19 Infection on Heart Failure and Anemia with Reference to Iron Metabolism Markers in an Adult Woman.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Nakamura Yuya, Ohsawa Isao, Goto Yoshikazu, Namba Hokuto, Dodo Yusuke, Tsuji Mayumi, Kiuchi Yuji, Inagaki Masahiro, Gotoh Hiromichi
Аннотация
A 35-year-old woman with fever, edema and rash was admitted. Pleural effusion and cardiomegaly were observed. A laboratory analysis revealed anemia with iron deficiency and elevated human parvovirus B19 (B19V) immunoglobulin M. The patient's hepcidin-25 and erythroferrone levels were not elevated compared to those observed later in her clinical course. On the other hand, her growth differentiation factor-15 (GDF-15) levels were elevated. She was diagnosed to have heart failure symptoms and anemia with specific iron metabolism abnormalities due to a B19V infection. After providing supportive treatment, the heart failure symptoms disappeared and her anemia had improved. This case emphasizes the need to include a B19V infection in the differential diagnosis when we encounter cases demonstrating reversible heart failure with anemia.