Ugeskrift for laeger · 2010
[Intravitreal ranibizumab for age-related macular degeneration].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Sørensen Torben Lykke, Kemp Henrik
Аннотация
INTRODUCTION: Ranibizumab has improved visual prognosis for patients with age-related macula degeneration (ARMD) complicated with choroidal neovascularisation. We evaluated the results of all our patients within a two-year period.
MATERIAL AND METHODS: A total of 647 eyes have so far been treated. In all 2,735 injections have been performed.
RESULTS: Ranibizumab initially increased significantly the best corrected visual acuity from 0.29 to 0.35 (p < 0.001), but after six and 12 months visual acuity stabilized (p = 0.1). We found a positive correlation between initial visual acuity and final visual acuity (p < 0.001). There was a negative correlation between age and final visual acuity (p < 0.001). Complications were rare: one got cataract, we observed a retinal detachment and one choroidal detachment. Other complications were rare and mild.
CONCLUSION: Ranibizumab improves visual prognosis in exudative ARMD. Intravitreal injections are safe and complications are rare.
MATERIAL AND METHODS: A total of 647 eyes have so far been treated. In all 2,735 injections have been performed.
RESULTS: Ranibizumab initially increased significantly the best corrected visual acuity from 0.29 to 0.35 (p < 0.001), but after six and 12 months visual acuity stabilized (p = 0.1). We found a positive correlation between initial visual acuity and final visual acuity (p < 0.001). There was a negative correlation between age and final visual acuity (p < 0.001). Complications were rare: one got cataract, we observed a retinal detachment and one choroidal detachment. Other complications were rare and mild.
CONCLUSION: Ranibizumab improves visual prognosis in exudative ARMD. Intravitreal injections are safe and complications are rare.