Cureus · 2024
A Rare Presentation of Glucose-6-Phosphate Dehydrogenase Deficiency.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Tyagi Neha, Premkumar Varsha, Patil Manojkumar G, Tambolkar Sampada, Mane Shailaja V
Аннотация
Approximately 400 million individuals globally experience glucose-6-phosphate dehydrogenase (G6PD) insufficiency, an enzymatic condition that may be hazardous. Because of mutations in the G6PD gene, which result in functional variants alongside a variety of biochemical and clinical symptoms, this condition is an X-linked hereditary genetic disorder. Our case is that of a 12-year-old male child who presented with acute liver failure and later on, exhibited signs of hemolysis as well. We had to rule out the possibilities of acetaminophen toxicity and hepatitis A before reaching the conclusion that an underlying G6PD deficiency was being exacerbated by viral infection and simultaneous ingestion of non-steroidal anti-inflammatory drugs (NSAIDs).