American journal of ophthalmology · 2006
Choroidal detachment following the use of tamsulosin (Flomax).
Клинический случайСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Shapiro Brett L, Petrovic Velimir, Lee Scott E, Flach Allan, McCaffery Sharon, O'Brien Joan M
Аннотация
PURPOSE: To report choroidal detachment following tamsulosin (Flomax, an alpha(1A)-adrenoceptor antagonist) treatment of benign prostatic hyperplasia (BPH).
DESIGN: Case report.
METHODS: Chart review, serial examination.
RESULTS: A 65-year-old man underwent uncomplicated cataract extraction and placement of a posterior chamber intraocular lens. The patient subsequently developed three separate episodes of choroidal detachments in the operated eye. Each episode was preceded by treatment with an alpha(1)-adrenoceptor antagonist.
CONCLUSIONS: Tamsulosin may cause adverse ocular effects including recurrent choroidal detachments. alpha(1A) is the dominant alpha-adrenoceptor in the rabbit choroid, and the mechanism for choroidal detachment in this patient could include some effect of antagonists like tamsulosin on these receptors.
DESIGN: Case report.
METHODS: Chart review, serial examination.
RESULTS: A 65-year-old man underwent uncomplicated cataract extraction and placement of a posterior chamber intraocular lens. The patient subsequently developed three separate episodes of choroidal detachments in the operated eye. Each episode was preceded by treatment with an alpha(1)-adrenoceptor antagonist.
CONCLUSIONS: Tamsulosin may cause adverse ocular effects including recurrent choroidal detachments. alpha(1A) is the dominant alpha-adrenoceptor in the rabbit choroid, and the mechanism for choroidal detachment in this patient could include some effect of antagonists like tamsulosin on these receptors.