Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India · 2021
Isolated Splenic Tuberculosis Masquerading as Disease Progression of Hodgkin's Lymphoma on Interim18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scan.
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Dey Sudip, Gupta Nitin, Verma Ritu, Seniaray Nikhil, Belho Ethel Shangne, Dhawan Shashi
Аннотация
18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) scan is the imaging modality of choice in the management of lymphoma. However, 18F-FDG is a nonspecific tracer for tumoral metabolic activity and infective pathology, thus posing a challenge in accurate response assessment. Here, we present a case of Hodgkin's lymphoma, referred for staging PET/CT scan which showed FDG-avid disease in the mediastinum, and on interim 18F-FDG PET/CT in addition to the mediastinal mass lesion, a FDG-avid lesion was also noted in the spleen suggestive of disease progression. The biopsy report of the lesion was tuberculosis, which was masquerading as disease progression on interim 18F-FDG PET/CT.