Clinical standards for antimicrobial stewardship in TB care.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Brehm T T, Akkerman O W, Sotgiu G, Tiberi S, Chang K-C, Dheda K, Duarte R, Vambe D, Udwadia Z F, Chesov D, Mendelson M, Iswari Saktiawati A M, van Ingen J, Eyuboglu F O, Tängdén T, Quang Vo L N, Riccardi N, Moschos C, Friedland J S, Lillebaek T, Chandy S J, Caminero J A, Thwaites G, Gandra S, Thursky K, George I A, Konstantynovska O, Fatima R, Yim J-J, Kwak N, Olaru I D, Gillespie S H, Kherabi Y, Perl S H, Grønningen E, Rodrigues C, Bjerrum S, Bange F, Cox V, Cirillo D M, Saluzzo F, Hara G L, Wagner D, Ismail N, Sloan D J, Eshun-Wilsonova I, Zeng M, Cantero C, Vasankari T, Mandalakas A, Kay A, Ness T, Torrico M M, Günther G, Kuksa L, Guglielmetti L, García-Basteiro A L, Marks G B, Pulcini C, Lange C
Аннотация
METHODS: An international panel of 62 experts participated in a Delphi process. Using a 5-point Likert scale (5 = strong agreement; 1 = strong disagreement), participants evaluated 10 draft clinical standards developed by a core coordination team. A standard was adopted if ≥90% of respondents rated it three or higher, according to a predefined consensus threshold.
RESULTS: All 10 standards reached the consensus threshold and were adopted: Standard 1, integration of TB into national AMR action plans; Standard 2, implementation of TB surveillance systems; Standard 3, education of health care providers, individuals affected by TB, and the public; Standard 4, integration of TB into AMS activities; Standard 5, establishment of expert consultation services; Standard 6, targeted testing and preventive treatment for individuals at risk for TB; Standard 7, access to timely and comprehensive drug susceptibility testing; Standard 8, prioritisation of efficacy, safety, and resistance prevention in TB treatment regimens; Standard 9, clinical and microbiological monitoring of treatment response; and Standard 10, assessment of adherence, drug exposure, and resistance in treatment failure.
CONCLUSION: These clinical standards aim to support clinicians, programme managers, and public health authorities in implementing effective, TB-specific AMS strategies.