International journal of molecular sciences · 2017
PET Imaging for Initial Staging and Therapy Assessment in Multiple Myeloma Patients.
СтатьяОбзорНазвание и аннотация: Перевод пока не подготовлен
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Bailly Clément, Leforestier Rodolphe, Jamet Bastien, Carlier Thomas, Bourgeois Mickael, Guérard François, Touzeau Cyrille, Moreau Philippe, Chérel Michel, Kraeber-Bodéré Françoise, Bodet-Milin Caroline
Аннотация
Multiple myeloma (MM) is a hematological neoplasm characterized by the clonal proliferation of malignant plasma cells in the bone marrow. MM results in diffuse or focal bone infiltration and extramedullary lesions. Over the past two decades, advances have been made with regard to the diagnosis, staging, treatment, and imaging of MM. Computed tomography (CT) and magnetic resonance imaging (MRI) are currently recommended as the most effective imaging modalities at diagnostic. Yet, recent data from the literature suggest that positron emission tomography combined with computed tomography (PET/CT) using 18F-deoxyglucose (FDG) is a promising technique for initial staging and therapeutic monitoring in this pathology. This paper reviews the recent advances as well as the potential place of a more specific radiopharmaceutical in MM.