Noneruption of teeth in amelogenesis imperfecta: A report of two cases and review.

Amelogenesis imperfecta (AI) comprises a complicated group of conditions, involving a structural defect of the tooth enamel, owing to certain genetic disturbances. It is expressed as an autosomal dominant, autosomal recessive or X-linked recessive trait. The structural pattern and clinical appearances of all the teeth, including those in the deciduous as well as the permanent dentition, are affected. It may be differentiated into three main divisions such as hypoplastic, hypocalcific and hypomaturative patterns. Eruption of tooth refers to a complex coordinated physiological process characterized by the movement of a tooth from its initial developmental position within the jaws to its final functional position in the occlusal plane, dictated crucially by dental follicle, bony remodeling metabolic alteration and molecular determinants. Alteration involving any one of the factors might cause hindrances. Herein, we report two cases with AI associated with noneruption.