JNMA; journal of the Nepal Medical Association · 2022
Recurrent Metastatic Choriocarcinoma Responsive to Etoposide and Cisplatin with Etoposide, Methotrexate, and Dactinomycin: A Case Report.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Das Sunil Kumar, Shahi Arun, Panthi Ram Chandra
Аннотация
UNLABELLED: Choriocarcinoma is a malignant trophoblastic tumour usually of placental origin. It is characterized by early metastasis to the brain and lungs. With early detection, it has a better prognosis with treatment. We report a case of 18 years female at 26 weeks of gestation in her third pregnancy who had a history of treatment for metastatic gestational trophoblastic neoplasm with chemotherapy and radiotherapy two years back. Therefore, she was managed as a case of recurrent choriocarcinoma with brain metastasis with chemotherapy (etoposide and cisplatin with etoposide, methotrexate, and dactinomycin) and was responsive. Her symptoms resolved and β-human chorionic gonadotropin dropped to normal value (<2.39 mIU/ml) which has shown that timely diagnosis and management can be vital for the successful treatment of brain metastasis.
KEYWORDS: chemotherapy; choriocarcinoma; metastasis; recurrence.
KEYWORDS: chemotherapy; choriocarcinoma; metastasis; recurrence.