Research Progress on Chemokine Signaling Pathways in Primary Immune Thrombocytopenia.

Primary immune thrombocytopenia (ITP) is an immune-mediated thrombocytopenic disorder with still insufficiently clear pathogenesis. The chemokine-chemokine receptor axis plays a crucial regulatory role in the immune system, and there is increasing evidence indicating its involvement in the onset and progression of ITP. This review summarizes and integrates existing studies on the chemokine-chemokine receptor axis and ITP, and explores its potential role in the pathogenesis and treatment of the disease.