Annales pharmaceutiques francaises · 2026
Hepatitis B in transition in Mauritania: HBsAg seroprevalence in patients attending the Cheikh Zayed National Hospital, Nouakchott (2019-2020).
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El Hachimi Hala, Yebouk Cheikh, Khiddi Fatimetou, El Alem Mohamed Mahmoud, Abdellahi Mohamed Vall Mohamed
Аннотация
BACKGROUND: Over a million people die each year from hepatitis B virus (HBV) infections, which are a serious global public health problem. More than seventy percent of adults in highly endemic areas, mainly in Africa and Southeast Asia, have signs of prior infection, and 7-20% of individuals are chronically infected. In Mauritania, hepatitis B is endemic, with infection rates ranging from 10 to 20%.
METHODS: A descriptive cross-sectional study was conducted between January 2019 and May 2020. Participants were recruited at Cheikh Zayed Hospital in Nouakchott. All patients presenting to the Cheikh Zaid Hospital laboratory for medical tests were recruited. Patients were referred by physicians from various hospital departments and provided informed consent prior to serological testing (HBsAg) for the detection of the hepatitis B virus surface antigen.
RESULTS: During the research period, from 1st January 2019 to 30th May 2020, 10,735 people were examined, and 1223 people (472 men and 751 women) were determined to be HBsAg positive, resulting in an overall seroprevalence of 11.4 percent. It is greater in males (12.9%) than in women (10.6%).
CONCLUSION: Following the introduction of hepatitis B vaccination and the strengthening of viral hepatitis control activities, a decrease in HBsAg seroprevalence was observed in this hospital population; however, this trend is probably multifactorial.
METHODS: A descriptive cross-sectional study was conducted between January 2019 and May 2020. Participants were recruited at Cheikh Zayed Hospital in Nouakchott. All patients presenting to the Cheikh Zaid Hospital laboratory for medical tests were recruited. Patients were referred by physicians from various hospital departments and provided informed consent prior to serological testing (HBsAg) for the detection of the hepatitis B virus surface antigen.
RESULTS: During the research period, from 1st January 2019 to 30th May 2020, 10,735 people were examined, and 1223 people (472 men and 751 women) were determined to be HBsAg positive, resulting in an overall seroprevalence of 11.4 percent. It is greater in males (12.9%) than in women (10.6%).
CONCLUSION: Following the introduction of hepatitis B vaccination and the strengthening of viral hepatitis control activities, a decrease in HBsAg seroprevalence was observed in this hospital population; however, this trend is probably multifactorial.