[Ultra-late phase of indocyanine green angiography in a case with metastatic choroidal tumor].

PURPOSE: To report a case with metastatic choroidal tumor evaluated with ultra-late phase of indocyanine green (ICG) angiography.

CASES: A 43-year-old woman had metastatic choroidal tumor originating from the thymus with an associated serous retinal detachment. ICG video-angiography demonstrated the tumor as hypofluorescent during the arterio-venous phase and hyperfluorescent during the conventional late phase (about 30 minutes after dye injection), and in the ultra-late phase (24 hours after dye injection). The original and metastatic tumors were treated by radiotherapy, resulting in flattening of the choroidal tumor and resolution of the serous retinal detachment. After the treatment, ICG angiography showed decay of ICG fluorescence and no apparent late accumulation of residual ICG in the tumor.

CONCLUSION

In a case with metastatic choroidal tumor, ICG dye accumulated in the tumor tissue before the treatment, but it decreased after treatment. This finding suggested that dye accumulation may be correlated with the tumor activity and requires a further study, enrolling patients with metastatic choroidal tumor for ICG angiographic evaluation.