Breast cancer (Tokyo, Japan) · 2013
Radiation recall dermatitis induced by trastuzumab.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Moon Dochang, Koo Ja Seung, Suh Chang-Ok, Yoon Chang Yun, Bae Jaehyun, Lee Soohyeon
Аннотация
We report a case of radiation recall dermatitis caused by trastuzumab. A 55-year-old woman with metastatic breast cancer received palliative first-line trastuzumab/paclitaxel and a salvage partial mastectomy with lymph node dissection was subsequently performed. In spite of the palliative setting, the pathology report indicated that no residual carcinoma was present, and then she underwent locoregional radiotherapy to ensure a definitive response. After radiotherapy, she has maintained trastuzumab monotherapy. Nine days after the fifth cycle of trastuzumab monotherapy, dermatitis in previously irradiated skin developed, with fever. Radiation recall dermatitis triggered by trastuzumab is extremely rare. A high fever developed abruptly with a skin rash. This may be the first case of this sort to be reported.