Impact of Alcohol Use on Nonalcohol-Related Liver Diseases.

Alcohol consumption remains a significant contributor to liver-related morbidity and mortality worldwide. This review explores the interplay between alcohol use and various liver conditions including viral hepatitis, hereditary hemochromatosis and secondary iron overload, autoimmune liver diseases, and rare disorders such as Wilson's disease, Fontan-associated liver disease, alpha-1 antitrypsin, noncirrhotic portal hypertension, and hepatic sarcoidosis. This review also addresses the management of alcohol use disorder in patients with chronic liver diseases as well as treatment considerations in patients who consume alcohol. With alcohol implicated in worsening outcomes across most liver conditions, abstinence is strongly recommended for patients with underlying liver diseases.