Zhurnal mikrobiologii, epidemiologii i immunobiologii · 2006
[Algorithm for prediction of reconvalescent salmonellosis carriage].
Аннотация на английскомСтатьяНазвание и аннотация: Оригинал на русском
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Chaĭnikova I N, Smoliagin A I, Valyshev A V, Skachkov M V, Brudastov Iu A, Bukharin O V
Аннотация
Of total of 181 patients with Salmonella infection were examined by clinical and laboratory methods. As many as 124 indices characterizing biological properties of Salmonellae, a large intestine microbiocenosis status, systemic and local immunity, were investigated as well. Among these indices, the most revealing signs were defined to prognosticate the reconvalescent carrier state. Conclusion was made on the prevalence of immune mechanisms in the development of reconvalescent salmonella carriage and on the important role of the ability of a causative agent to inactivate the factors of host innate immunity in this process. Diagnostic prognosis algorithm for Salmonella bacterial carriage was worked out. Clinical testing confirmed its effectiveness.