European respiratory review : an official journal of the European Respiratory Society · 2013
Small airways diseases, excluding asthma and COPD: an overview.
Conference ProceedingsНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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Burgel Pierre-Régis, Bergeron Anne, de Blic Jacques, Bonniaud Philippe, Bourdin Arnaud, Chanez Pascal, Chinet Thierry, Dalphin Jean-Charles, Devillier Philippe, Deschildre Antoine, Didier Alain, Kambouchner Marianne, Knoop Christiane, Laurent François, Nunes Hilario, Perez Thierry, Roche Nicolas, Tillie-Leblond Isabelle, Dusser Daniel
Аннотация
This review is the summary of a workshop on small airways disease, which took place in Porquerolles, France in November 2011. The purpose of this workshop was to review the evidence on small airways (bronchiolar) involvement under various pathophysiological circumstances, excluding asthma and chronic obstructive pulmonary disease. Histopathological patterns associated with small airways disease were reviewed, including cellular and obliterative bronchiolitis. Many pathophysiological conditions have been associated with small airways disease including airway infections, connective tissue diseases and inflammatory bowel diseases, bone marrow and lung transplantation, common variable immunodeficiency disorders, diffuse panbronchiolitis, and diseases related to environmental exposures to pollutants, allergens and drugs. Pathogenesis, clinical presentation, a computed tomography scan and pulmonary function test findings are reviewed, and therapeutic options are described with the objective of providing an integrative approach to these disorders.