Therapies and Pipeline for Hepatitis B and Hepatitis D.

This article provides a comprehensive overview of the current therapeutic approaches to managing hepatitis B virus infection. It begins with an outline of the goals of treatment, including viral suppression and prevention of liver disease progression. The article then delves into the current classes of antiviral agents used in clinical practice, such as nucleos(t)ide analogs (eg, tenofovir and entecavir) and pegylated interferon. The article then covers emerging therapies and novel agents under investigation, including capsid/core inhibitors, immune modulators, gene editing, and therapeutic vaccines. This article aims to inform health care professionals regarding the evolving landscape of hepatitis B treatment.