Is Laundry Detergent a Common Cause of Allergic Contact Dermatitis?

Both patients and health care providers commonly suspect laundry detergent as the cause of skin problems; however, research suggests that the prevalence of laundry detergent-associated allergic contact dermatitis (ACD) may be quite low. Herein, we provide a summary of the evidence for the potential allergenicity of laundry detergent, including common allergens present in laundry detergent, the role of machine washing, and the differential diagnosis for laundry detergent-associated ACD.