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DOI 10.2217/fmb-2020-0238

Медицинская библиотека · Future microbiology · 2021

Tuberculosis treatment outcomes in a rural area of Senegal: a decade of experience from 2010 to 2019 by StopTB Italia.

Riccardi Niccolò, Villa Simone, Giacomelli Andrea, Diaw Mama M, Ndiaye Mamoud, Gning Lamine, Robbiano Marta, Alagna Riccardo, Saderi Laura, Biagio Antonio Di, Bassetti Matteo, Cirillo Daniela M, Sotgiu Giovanni, Codecasa Luigi R, Sarr Marie, Besozzi Giorgio

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Аннотация

Background

Tuberculosis (TB) unevenly affects individuals across the globe, especially in rural areas of low-income countries. Aim of the study was to assess the impact of social protection to increase TB awareness on treatment outcomes among TB patients in a rural area of Senegal. Materials & methods: The study, conducted in Fimela district (Senegal) from 1 January 2010 to 31 December 2019 and the intervention started from 31 January 2013, includes activities to increase awareness, active case finding, active follow-up and social protection.

Results

Overall, 435 subjects - mainly male and young - were included in the analysis. Among TB cases, 94% had pulmonary involvement, 87% had no previous TB history, and 6% resulted positive HIV. Improved outcome was observed once intervention began (from 71 to 91%, p < 0.001); whereas mortality decreased (from 15 to 5%; p < 0.001), especially for those HIV co-infected for whom TB mortality rate dropped from 70 to 29%.

Conclusion

After beginning the cooperation program, TB treatment success increased as a result of the decline of mortality, especially in people living with HIV.

Для цитирования: Riccardi Niccolò, Villa Simone, Giacomelli Andrea, Diaw Mama M, Ndiaye Mamoud, Gning Lamine, Robbiano Marta, Alagna Riccardo, Saderi Laura, Biagio Antonio Di, Bassetti Matteo, Cirillo Daniela M, Sotgiu Giovanni, Codecasa Luigi R, Sarr Marie, Besozzi Giorgio. Tuberculosis treatment outcomes in a rural area of Senegal: a decade of experience from 2010 to 2019 by StopTB Italia.. Future microbiology. 2021. DOI: 10.2217/fmb-2020-0238.

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