The Israel Medical Association journal : IMAJ · 2020
Transbronchial Cryobiopsy in Diffuse Parenchymal Lung Diseases in a Community Medical Center.
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Shkeiri Rashed, Schneer Sonia, Avarmovich Amir, Adir Yochai
Аннотация
BACKGROUND: Transbronchial cryobiopsy (TBC) has recently emerged for the assessment of diffuse parenchymal lung disease (DPLD) as a less invasive procedure than surgical lung biopsy. The diagnostic usefulness and safety of TBC is still controversial.
OBJECTIVES: To evaluate the safety and diagnostic yield of TBC in a peripheral community medical center.
METHODS: We retrospectively reviewed the charts of all patients with DPLD who underwent TBC from January 2015 to January 2020.
RESULTS: The study comprised 97 patients. Three samples were taken from each patient with an average diameter of 0.59 cm. The histologic diagnostic yield was 54% (52 of 97 procedures). The most frequent histopathologic diagnoses were usual interstitial pneumonia in 13 patients (13%). Bleeding was observed in 19 cases (19%) and only one patient (1%) had severe bleeding. Pneumothorax developed in seven patients (7%) and one patient (1%) suffered from Interstitial lung disease exacerbation.
CONCLUSIONS: TBC was found to be safe; however, the diagnostic yield was rather low compared to other studies, which emphasizes the need for interstitial lung disease centers with expert in this field.
OBJECTIVES: To evaluate the safety and diagnostic yield of TBC in a peripheral community medical center.
METHODS: We retrospectively reviewed the charts of all patients with DPLD who underwent TBC from January 2015 to January 2020.
RESULTS: The study comprised 97 patients. Three samples were taken from each patient with an average diameter of 0.59 cm. The histologic diagnostic yield was 54% (52 of 97 procedures). The most frequent histopathologic diagnoses were usual interstitial pneumonia in 13 patients (13%). Bleeding was observed in 19 cases (19%) and only one patient (1%) had severe bleeding. Pneumothorax developed in seven patients (7%) and one patient (1%) suffered from Interstitial lung disease exacerbation.
CONCLUSIONS: TBC was found to be safe; however, the diagnostic yield was rather low compared to other studies, which emphasizes the need for interstitial lung disease centers with expert in this field.