Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2009
Growing vestibular schwannomas: what happens next?
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Mick Paul, Westerberg Brian D, Ngo Raymond, Akagami Ryojo
Аннотация
OBJECTIVE: To determine the subsequent growth patterns in vestibular schwannomas shown to be growing on serial imaging.
STUDY DESIGN: Retrospective review.
SETTING: Tertiary academic referral center.
PATIENTS: Patients with tumors that demonstrated growth of greater than 1 mm/yr between 2 consecutive scans (magnetic resonance or computed tomography) and had at least 1 follow-up scan were included. Patients with neurofibromatosis were excluded.
INTERVENTION(S): Review of radiographic images (magnetic resonance imaging scans) or neuroradiologists' reports when the images were unavailable.
MAIN OUTCOME MEASURE(S): Maximum dimension along the axis of the internal auditory canal was measured for intracanalicular tumors, whereas for extracanalicular tumors, maximal dimension along any orientation was used. A significant difference in dimension was defined to be greater than 1 mm/yr, positive or negative.
RESULTS: Thirty-six patients were included in the study; 47% were women and with an average age of 60.2 years. The average follow-up period after growth was identified was 2.1 years. Of the growing tumors, 63.9% continued to grow, 30.6% stayed the same size, and 5.6% regressed in size.
CONCLUSION: Most vestibular schwannomas identified to be growing are likely to continue to grow on subsequent serial imaging. These results are useful in clinical decision making and counseling patients with growing vestibular schwannomas.
STUDY DESIGN: Retrospective review.
SETTING: Tertiary academic referral center.
PATIENTS: Patients with tumors that demonstrated growth of greater than 1 mm/yr between 2 consecutive scans (magnetic resonance or computed tomography) and had at least 1 follow-up scan were included. Patients with neurofibromatosis were excluded.
INTERVENTION(S): Review of radiographic images (magnetic resonance imaging scans) or neuroradiologists' reports when the images were unavailable.
MAIN OUTCOME MEASURE(S): Maximum dimension along the axis of the internal auditory canal was measured for intracanalicular tumors, whereas for extracanalicular tumors, maximal dimension along any orientation was used. A significant difference in dimension was defined to be greater than 1 mm/yr, positive or negative.
RESULTS: Thirty-six patients were included in the study; 47% were women and with an average age of 60.2 years. The average follow-up period after growth was identified was 2.1 years. Of the growing tumors, 63.9% continued to grow, 30.6% stayed the same size, and 5.6% regressed in size.
CONCLUSION: Most vestibular schwannomas identified to be growing are likely to continue to grow on subsequent serial imaging. These results are useful in clinical decision making and counseling patients with growing vestibular schwannomas.