Current treatments and the future of nanomedicine in hepatitis C.

Despite recent advances in hepatitis C treatment, the disease remains a significant global health burden, with an estimated 1 million new infections in 2022. Upon infection, the disease will progress to chronic infection, leading to cirrhosis, fibrosis, hepatocellular carcinoma, and end-stage liver disease. Although treatments (Direct-Acting Antiretrovirals) are available, they cannot completely clear the virus. In this review, we summarized the current therapies used to treat hepatitis C, followed by an analysis of the future application of nanomedicine to combat this disease. We compile information related to gene silencing, the nanodelivery of specific drugs, and the trials associated with vaccine development. Although many studies have been successful in animal models, further research is needed to develop a cure or vaccine.