Scandinavian cardiovascular journal : SCJ · 2003
Early results of a new mechanical tri-leaflet heart valve prosthesis--"Tricusp": an animal study.
Оценочное исследованиеСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Pehrsson S Kenneth, Eriksson Maria J, Lentell Jan C, Bowald Staffan
Аннотация
OBJECTIVE: A new tri-leaflet mechanical heart valve made of titanium was inserted in the mitral position to evaluate early results.
METHODS AND RESULTS: Five sheep were followed between 3 and 6 months (mean 4.7 months) and performed very well clinically during the follow-up period. In three of five animals a minor para-valvular leakage without hemodynamic importance was observed. The invasive pressure measurements at the end of follow-up revealed only minor transvalvular pressure differences between 1 and 4 mmHg (mean 2.4 mmHg). Similar results were obtained by echo-Doppler technique. Histological examination of the tissue around the valve showed no signs of foreign body reaction or chronic inflammatory reaction.
CONCLUSION: This new tri-leaflet heart valve has shown an excellent hemodynamic performance and good tissue compatibility, and therefore may be an alternative to other currently used valve prostheses.
METHODS AND RESULTS: Five sheep were followed between 3 and 6 months (mean 4.7 months) and performed very well clinically during the follow-up period. In three of five animals a minor para-valvular leakage without hemodynamic importance was observed. The invasive pressure measurements at the end of follow-up revealed only minor transvalvular pressure differences between 1 and 4 mmHg (mean 2.4 mmHg). Similar results were obtained by echo-Doppler technique. Histological examination of the tissue around the valve showed no signs of foreign body reaction or chronic inflammatory reaction.
CONCLUSION: This new tri-leaflet heart valve has shown an excellent hemodynamic performance and good tissue compatibility, and therefore may be an alternative to other currently used valve prostheses.
Предметные рубрики MeSH
AnimalsAutopsyDisease Models, AnimalEchocardiography, Doppler, ColorFollow-Up StudiesHeart Valve ProsthesisHeart Valve Prosthesis ImplantationMinimally Invasive Surgical ProceduresMitral ValveMitral Valve InsufficiencyModels, CardiovascularProsthesis DesignSeverity of Illness IndexSheepTime FactorsTreatment OutcomeTricuspid Valve