Медицинская библиотека · Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2012

Retinal vessel changes after laser treatment for retinopathy of prematurity.

Kwon Julie Y, Ghodasra Devon H, Karp Karen A, Ying Gui-shuang, Wilson Clare M, Huang Jiayan, Mills Monte D, Fielder Alistair R, Quinn Graham E

СтатьяПоддержка исследования: вне правительства СШАПеревод пока не подготовлен

Аннотация

BACKGROUND

The clinical response to retinopathy of prematurity (ROP) treatment is currently assessed subjectively. This study aims to quantify treatment response objectively by assessing changes in digital images of posterior pole retinal vessel width and tortuosity.

METHODS

Images of 30 right eyes with type 1 ROP obtained at up to three time points were analyzed: before treatment (T = 0) and 1 (T = 1) and/or 2 weeks (T = 2) after treatment. Width and tortuosity of retinal vessels were analyzed from digital images using computer-assisted image analysis software.

RESULTS

Vessel width decreased by 20% (P < 0.004) within the first week and remained stable by the second week after laser treatment. Vessel tortuosity did not significantly change by the first week but decreased 27% (P < 0.01) by second week.

CONCLUSIONS

Vessel width appears to decrease dramatic within the first week, whereas the regression of tortuosity follows a slower course.

Для цитирования: Kwon Julie Y, Ghodasra Devon H, Karp Karen A, Ying Gui-shuang, Wilson Clare M, Huang Jiayan, Mills Monte D, Fielder Alistair R, Quinn Graham E. Retinal vessel changes after laser treatment for retinopathy of prematurity.. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus. 2012. DOI: 10.1016/j.jaapos.2012.04.002.

Предметные рубрики MeSH

Arterioles Female Gestational Age Humans Image Processing, Computer-Assisted Infant, Newborn Infant, Very Low Birth Weight Laser Coagulation Male Pilot Projects Retinal Vessels Retinopathy of Prematurity Treatment Outcome Venules

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