BMJ (Clinical research ed.) · 1992
Vitamin C depletion and pressure sores in elderly patients with femoral neck fracture.
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Goode H F, Burns E, Walker B E
Аннотация
OBJECTIVE: To evaluate the contribution of specific nutritional deficiencies (as indicated by zinc; vitamin A, C, and E; albumin; and haemoglobin concentrations) to the risk of pressure sores.
DESIGN: Observational cohort study.
SETTING: St James's University Hospital, Leeds.
SUBJECTS: 21 elderly patients presenting consecutively to the orthopaedic unit with femoral neck fracture.
MAIN OUTCOME MEASURE: Full thickness epidermal break over a pressure bearing surface.
RESULTS: 10 patients (48%) developed a pressure sore during their hospital stay. Indices of zinc status and concentrations of albumin, haemoglobin, and vitamins A and E were similar in patients who developed a pressure sore and those who did not. Mean leucocyte vitamin C concentration, however, was 6.3 (SD 2.2) micrograms/10(8) cells in patients who developed a pressure sore as compared with 12.8 (4.6) micrograms/10(8) cells in patients who did not.
CONCLUSIONS: Low concentrations of leucocyte vitamin C appear to be associated with subsequent development of pressure sores in elderly patients with femoral neck fractures.
DESIGN: Observational cohort study.
SETTING: St James's University Hospital, Leeds.
SUBJECTS: 21 elderly patients presenting consecutively to the orthopaedic unit with femoral neck fracture.
MAIN OUTCOME MEASURE: Full thickness epidermal break over a pressure bearing surface.
RESULTS: 10 patients (48%) developed a pressure sore during their hospital stay. Indices of zinc status and concentrations of albumin, haemoglobin, and vitamins A and E were similar in patients who developed a pressure sore and those who did not. Mean leucocyte vitamin C concentration, however, was 6.3 (SD 2.2) micrograms/10(8) cells in patients who developed a pressure sore as compared with 12.8 (4.6) micrograms/10(8) cells in patients who did not.
CONCLUSIONS: Low concentrations of leucocyte vitamin C appear to be associated with subsequent development of pressure sores in elderly patients with femoral neck fractures.