Reviews in medical virology · 2020
Current pharmacological modalities for management of novel coronavirus disease 2019 (COVID-19) and the rationale for their utilization: A review.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Giovane Richard A, Rezai Shadi, Cleland Ellen, Henderson Cassandra E
Аннотация
SARS-CoV-2 has caused a pandemic which is putting strain on the health-care system and global economy. There is much pressure to develop both preventative and curative therapies for SARS-CoV-2 as there is no evidence to support therapies to improve outcomes in patients with SARS-CoV-2. Medications that inhibit certain steps of virus life cycle that are currently used to treat other illnesses such as Malaria, Ebola, HIV and Hepatitis C are being studied for use against SARS-CoV-2. To date, data is limited for medications that facilitate clinical improvement of COVID-19 infections.
Предметные рубрики MeSH
Adenosine MonophosphateAlanineAngiotensin-Converting Enzyme 2Antibodies, Monoclonal, HumanizedAntiviral AgentsBetacoronavirusCOVID-19Coronavirus InfectionsDisease ProgressionDrug CombinationsDrug RepositioningEstersGabexateGene Expression RegulationGuanidinesHost-Pathogen InteractionsHumansHydroxychloroquineIndolesLopinavirPandemicsPeptidyl-Dipeptidase APneumonia, ViralRitonavirSARS-CoV-2Spike Glycoprotein, CoronavirusSulfides