Vaccine · 2008
Vaccination coverage and awareness of infectious risks in patients with an absent or dysfunctional spleen in the Netherlands.
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Meerveld-Eggink A, de Weerdt O, Rijkers G T, van Velzen-Blad H, Biesma D H
Аннотация
OBJECTIVE: To evaluate the current practice to prevent infections in patients with an absent or dysfunctional spleen in a part of the Netherlands. To measure serum antibody levels against Streptococcus pneumoniae and Haemophilus influenzae type b.
DESIGN: Observational study of vaccination coverage by analysis of questionnaires and serum antibody levels.
SETTING: Primary care practices in the Utrecht area of the Netherlands, catchment area 750,000 inhabitants, period 2006-2007.
PARTICIPANTS: One hundred and thirty adult patients with an absent or dysfunctional spleen.
MAIN OUTCOME MEASURES: Percentage of patients informed about infectious risks and aware of the timely use of antimicrobial prophylaxis. Vaccine coverage against S. pneumoniae, H. influenzae type b and Neisseria meningitidis. Levels of serum antibodies against S. pneumoniae and H. influenzae type b.
RESULTS: Fifty-six patients (43%) have not received up-to-date information about the infectious risks associated with their condition; 65 patients (50%) are not aware of the need to contact a physician immediately in case of high fever; 37 patients (28%) are keeping antimicrobial prophylaxis at home. Pneumococcal vaccination has been administered within the last 5 years to 103 of 130 patients, antibody levels above the threshold of > or =0.35microg/mL are found in 83 of the 101 patients (data lacking in 2 patients). Complete coverage against S. pneumoniae is only 64% (83/130). A minority of patients (respectively 32% and 27%) has been vaccinated against H. influenzae type b and N. meningitidis.
CONCLUSIONS: Vaccination coverage and education about infectious risks in patients with an absent or dysfunctional spleen can be improved markedly in the Netherlands.
DESIGN: Observational study of vaccination coverage by analysis of questionnaires and serum antibody levels.
SETTING: Primary care practices in the Utrecht area of the Netherlands, catchment area 750,000 inhabitants, period 2006-2007.
PARTICIPANTS: One hundred and thirty adult patients with an absent or dysfunctional spleen.
MAIN OUTCOME MEASURES: Percentage of patients informed about infectious risks and aware of the timely use of antimicrobial prophylaxis. Vaccine coverage against S. pneumoniae, H. influenzae type b and Neisseria meningitidis. Levels of serum antibodies against S. pneumoniae and H. influenzae type b.
RESULTS: Fifty-six patients (43%) have not received up-to-date information about the infectious risks associated with their condition; 65 patients (50%) are not aware of the need to contact a physician immediately in case of high fever; 37 patients (28%) are keeping antimicrobial prophylaxis at home. Pneumococcal vaccination has been administered within the last 5 years to 103 of 130 patients, antibody levels above the threshold of > or =0.35microg/mL are found in 83 of the 101 patients (data lacking in 2 patients). Complete coverage against S. pneumoniae is only 64% (83/130). A minority of patients (respectively 32% and 27%) has been vaccinated against H. influenzae type b and N. meningitidis.
CONCLUSIONS: Vaccination coverage and education about infectious risks in patients with an absent or dysfunctional spleen can be improved markedly in the Netherlands.