[Curative effect analysis of radical endoscopic sinus surgery for eosinophilic chronic rhinosinusitis with nasal polyps].

Objective:To evaluate the efficacy of functional endoscopic sinus surgery（FESS） and radical endoscopic sinus surgery（RESS） in eosinophilic chronic sinusitis with nasal polyps（EosCRSwNP）. Methods:A total of 44 patients diagnosed with EosCRSwNP in the Department of Otorhinolaryngology Head and Neck Surgery, Henan Provincial People's Hospital from July 1st, 2020 to August 1st, 2021 were included, the percentage of eosinophils in leukocytes in all patients included was more than 3.05%. The patients were randomly divided into FESS group and RESS group according to random number table. The visual analogue scale （VAS） score, Lund-Kennedy score and sino-nasal outcome test-22 （SNOT-22） were compared between the two groups before operation, 1 month, 3 months, 6 months and 1 year after operation. Results:At 1 year after operation, the scores of the two groups were significantly improved compared with those before operation, and the differences were statistically significant （P<0.01）. There were significant differences in nasal endoscopic score, VAS score and SNOT-22 score between the two groups（P=0.01, P=0.03, P=0.03）. The recurrence rate of RESS group was 26.09%（6/23） and that of FESS group was 61.90%（13/21）, and the difference was statistically significant（P=0.04）. Conclusion:Both RESS and FESS can improve nasal symptoms and promote olfactory recovery in EosCRSwNP patients, but RESS has more advantages in reducing recurrence and improving the prognosis of patients.